Paget’s disease of the bone (osteitis deformans) is a chronic bone disorder characterized by excessive breakdown and regrowth in the affected bone(s). Many people have no symptoms. The disease is more common as you age and is uncommon in people under the age of 50.
Involvement of multiple bones (polyostotic) is more common than single or monostotic disease .
Polyostotic disease is more prevalent than monostotic type. The most frequent sites of involvement are:
The cause of Paget's bone disease is unknown. Scientists suspect a combination of environmental and genetic factors contribute to the disease. Several genes appear to be linked to getting the disease.
Some scientists believe Paget's disease of bone is related to a viral infection in your bone cells, but this theory is controversial.
The following tests help to diagnose Paget’s disease of the bone:
Bone scan: Providers sometimes use bone scans to see which bone(s) are affected by Paget’s disease and how mild or severe it is. During a bone scan, a safe amount of radioactive liquid is injected into your vein. The liquid then flows through your bloodstream and into your bones and makes areas of the bone affected by Paget’s disease appear “bright” on the images your bones.
This condition will be rated on limitation of motion of affected body part.
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